If you’re exploring microneedling for hair loss, you’ve likely come across the debate of 16 vs 36 pin for hair loss. The number of pins in a microneedling cartridge can affect your results, comfort, and healing.
This guide breaks down the key differences between the two, helping you choose the best option for scalp stimulation and hair regrowth. Learn how each cartridge works, when to use them, and what experts recommend — all in one medically backed, easy-to-follow post.

What Is Microneedling for Hair Loss?
Microneedling, also called collagen induction therapy, involves creating controlled micro-injuries in the skin to stimulate healing. When applied to the scalp, this process encourages hair follicles to grow by increasing blood flow, triggering collagen production, and improving product absorption.
How It Works
- Tiny needles puncture the scalp, initiating a healing response.
- Growth factors and stem cells are activated.
- Scalp circulation improves, reviving dormant hair follicles.
Key Benefits for Hair Regrowth
- Boosts natural collagen and elastin production
- Improves absorption of hair growth serums like Minoxidil
- Non-invasive, minimal downtime
- Can be combined with PRP therapy for enhanced results
Devices and Cartridge Types Used
Most devices like Dermapens or microneedling pens use interchangeable needle cartridges. These vary by pin count, typically ranging from 12, 16, or 36 pins — which affects the intensity and effectiveness of each session.
16 vs 36 Pin Microneedling Cartridges: What’s the Difference?
Choosing between a 16-pin and a 36-pin microneedling cartridge isn’t just about numbers — it’s about precision, penetration, and purpose.
Number of Pins and Needle Density
- 16 Pin: Fewer needles, more space between each, providing deeper penetration per pin.
- 36 Pin: More needles, denser configuration, shallower depth per needle.
Pro Tip: 16-pin cartridges are often preferred for targeted, deeper stimulation on the scalp.
Depth Penetration and Skin Impact
- 16-pin cartridges typically allow for deeper penetration, stimulating the dermis more effectively for hair growth.
- 36-pin cartridges focus on surface-level stimulation, which may be better for skincare than scalp treatments.
Treatment Time and Coverage Area
- 36-pin covers larger surface area faster, which is ideal for short, shallow sessions.
- 16-pin takes longer but provides more concentrated impact in each pass.
Pain and Discomfort Levels
- 36-pin may feel gentler due to shallow penetration.
- 16-pin may cause slightly more discomfort but often yields better results for thick scalp skin.
Results on Hair Regrowth Over Time
Studies and anecdotal evidence suggest that deeper microneedling (as seen with 16-pin devices) stimulates stronger hair regrowth, particularly when combined with topicals or PRP.
Which Is Better for Hair Loss: 16 Pin or 36 Pin?
Expert Opinion on Pin Counts
According to trichologists and hair restoration specialists like Dr. Rana Irfan (ABHRS-certified in Islamabad), 16-pin cartridges offer greater dermal stimulation, making them ideal for treating androgenetic alopecia or thinning crowns.
Best Option Based on Hair Loss Severity
- Mild Hair Thinning: 36-pin may suffice for maintenance.
- Moderate to Severe Hair Loss: 16-pin offers better follicle activation.
Skin Sensitivity and Scalp Health Considerations
- Sensitive or inflamed scalps may respond better to 36-pin.
- Normal to oily scalps with resilient skin are good candidates for 16-pin.
When to Use 16 Pin vs 36 Pin Microneedling Cartridges
For Beginners and Sensitive Scalps
If you’re new to microneedling or have a sensitive scalp, the 36-pin cartridge may offer a gentler introduction.
For Advanced Users or Clinical Settings
Professionals often use 16-pin cartridges in clinical settings to achieve deeper stimulation and combine them with treatments like PRP or growth factor serums.
Combination Approach with PRP or Minoxidil
- 16-pin + PRP = Maximum follicle stimulation
- 36-pin + Minoxidil = Maintenance and absorption enhancement
- Alternate between both in different sessions for best outcomes
Expert Tips for Effective Microneedling at Home
Choosing the Right Dermapen Device
Look for:
- Adjustable needle depth (0.5–1.5mm for scalp)
- Medical-grade cartridges (preferably 16-pin for hair loss)
- Wireless or rechargeable options for ease of use
Proper Needle Depth and Session Frequency
- Start with 0.5mm depth, increase gradually
- Frequency: Once every 7–10 days
- Avoid daily use overuse can cause inflammation
Pre- and Post-Treatment Scalp Care
- Clean scalp thoroughly before treatment
- Use alcohol-free serums or PRP immediately after
- Avoid shampooing for 12 hours
- No sun exposure or sweating for 24–48 hours
Common Mistakes to Avoid
- Using excessive pressure
- Skipping sterilization
- Not replacing cartridges
- Microneedling over inflamed or infected scalp
Are There Any Side Effects or Risks?
Short-Term Irritation or Redness
Mild redness or tingling is normal and should subside in 24–48 hours.
Infections or Improper Use Risks
Using non-sterile cartridges or incorrect technique may result in folliculitis or infections.
When to Seek Medical Advice
- Persistent redness or swelling
- Bleeding beyond minor pinpoints
- Allergic reactions to topicals
Which Cartridge Should You Choose?
Summary of Pros and Cons
Feature | 16-Pin Cartridge | 36-Pin Cartridge |
---|---|---|
Penetration Depth | Deeper | Shallower |
Coverage Area | Smaller | Larger |
Comfort Level | Slightly less | More gentle |
Ideal For | Advanced users / PRP | Beginners / Maintenance |
Best Use | Thick scalp, moderate-severe hair loss | Sensitive scalp, light stimulation |

FAQs about 16 vs 36 Pin for Hair Loss
Is 36 pin more effective than 16 pin?
Not necessarily. While it covers more area, it provides shallower stimulation, making 16-pin cartridges more effective for deeper hair follicle activation.
Can I switch between 16 and 36 pin microneedling?
Yes. Some users alternate between them based on sensitivity or treatment goals.
How often should I microneedle with each type?
16-pin: Every 7–10 days
36-pin: Every 5–7 days, if using for product absorption
Which pin count is best with PRP or topical serums?
16-pin is best with PRP for deeper absorption. 36-pin works well with lightweight serums like Minoxidil.
Take Your Next Step
Choosing between 16 and 36 pin microneedling cartridges can be confusing — but you don’t have to figure it out alone. At Dr. Rana Irfan’s Hair Restoration Clinic in Islamabad, we offer customized hair restoration services plans using medical-grade devices tailored to your scalp and hair loss type.
Book a consultation with Dr. Rana Irfan today to get expert guidance, safe treatment, and real results.